17973-86-3, 3,6-Dibromopyridazine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1) In a 250ml three-vial bottle,Weigh 0.05 mol of 3,6-dibromopyridazine,0.06 mol (3,5-di-tert-butylphenyl) boric acid,100ml toluene,Stir and dissolve,Under nitrogen protection,Add 0.0025mol Pd(PPh3)4,0.1mol potassium carbonate,50 ml water and ethanol volume ratio of 1:1 mixture,Stir and warm up to 120C,Reflux reaction for 12 hours,Sampling point board,Shows no remaining 3,6-dibromopyridazine,Complete reaction;Naturally cool to room temperaturefilter,Layered filtrate,Take the organic phase and vortex it to zero fraction.Over neutral silica gel column,Intermediate 2-1 is obtained,HPLC purity 99.3%,Yield 61.2%;
17973-86-3, As the paragraph descriping shows that 17973-86-3 is playing an increasingly important role.
Reference£º
Patent; Jiangsu March Optoelectric Technology Co., Ltd.; Xu Kai; Li Chong; Zhang Xiaoqing; Zhang Zhaochao; (45 pag.)CN107880028; (2018); A;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem