20744-39-2, Pyridazin-4-amine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a mixture of 27 (500 mg, 1.39 mmol), 4-aminopyridazine (159 mg, 1.67 mmol) and K3PO4 (355 mg, 1.67 mmol) in DMSO (8 mL) were added CuI (318 mg, 1.67 mmol) and N,N’-dimethylethylenediamine (0.18 mL, 1.67 mmol), and the mixture was stirred at 110 C for 30 min under an argon gas atmosphere. After cooling atroom temperature, the mixture was diluted with water and 28% aqueous ammonia solution, and extracted with EtOAc. The organic layer was washed with brine, dried over MgSO4, filtered and concentrated in vacuo. The residue was purified by silica gel column chromatography (0-5% MeOH in CHCl3) to give 30f (138 mg, 27%) as a yellow solid. 1H NMR (CDCl3) delta 5.47 (s,2H), 6.80 (dd, 1H, J = 9.4, 2.6 Hz), 6.90 (dd, 1H, J = 5.9, 2.9 Hz), 7.07 (d, 1H, J = 2.6 Hz), 7.57-7.64 (m, 2H), 7.78-7.84 (m, 1H), 7.87 (d, 1H, J = 8.1 Hz), 8.05 (d, 1H, J = 8.6 Hz), 8.22-8.27 (m, 2H), 8.59 (br s, 1H), 9.08 (br s, 1H), 9.58 (s, 1H); MS (ESI) m/z 374 [M+H]+., 20744-39-2
As the paragraph descriping shows that 20744-39-2 is playing an increasingly important role.
Reference£º
Article; Hamaguchi, Wataru; Masuda, Naoyuki; Isomura, Mai; Miyamoto, Satoshi; Kikuchi, Shigetoshi; Amano, Yasushi; Honbou, Kazuya; Mihara, Takuma; Watanabe, Toshihiro; Bioorganic and Medicinal Chemistry; vol. 21; 24; (2013); p. 7612 – 7623;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem