50681-25-9, 4-Pyridazinecarboxylic Acid is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
50681-25-9, EXAMPLE 11 [1S-(1R*,2S*,3S*)]-N-[4-[(Butylamino)sulfonyl]-1-(cyclohexylmethyl)-2,3-dihydroxybutyl]-4-pyridazinecarboxamide Following the procedure of Example 6 but employing molar equivalent amounts of 4-pyridazine carboxylic acid (33 mg., 0.268 mmole, 1 eq.) and the product of Example 1 (100 mg., 0.268 mmole, 1 eq.), 31 mg. of white solid [1S-(1R*,2S*,3S*)]-N-[4-[(butylamino)sulfonyl]-1-(cyclohexylmethyl)-2,3-dihydroxybutyl]-4-pyridazinecarboxamide were obtained; m.p. 170-172; [alpha]D =-29.1 (c=0.43, methanol). TLC (silica gel; 10% methanol in dichloromethane containing 0.2% NH4 OH) Rf =0.46.
As the paragraph descriping shows that 50681-25-9 is playing an increasingly important role.
Reference£º
Patent; E. R. Squibb & Sons, Inc.; US5098924; (1992); A;,
Pyridazine – Wikipedia
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