Downstream synthetic route of 51149-08-7

51149-08-7 3,6-Dichloropyridazine-4-carboxylic acid 433804, apyridazine compound, is more and more widely used in various fields.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.51149-08-7,3,6-Dichloropyridazine-4-carboxylic acid,as a common compound, the synthetic route is as follows.,51149-08-7

Method for svnthesising A. If and A. Ig; 3,6-dichloro-pyridazine-4-carboxylic acid (4.0 g, 20.7 mmol) is taken up in dioxane, combined with HCl (20.7 niL, IM in H2O) and stirred for 4 h at 90C. The precipitate formed is filtered off, dried and 6-chloro-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid is obtained.

51149-08-7 3,6-Dichloropyridazine-4-carboxylic acid 433804, apyridazine compound, is more and more widely used in various fields.

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ENGELHARDT, Harald; BOEHMELT, Guido; KOFINK, Christiane; KUHN, Daniel; McCONNELL, Darryl; STADTMUELLER, Heinz; WO2010/7114; (2010); A2;,
Pyridazine – Wikipedia
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