With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1120-95-2,3-Chloropyridazine,as a common compound, the synthetic route is as follows.
A mixture of 2-cloropyridazine (3 eq.) and 1,4 cyclohexane methyl amine (1 eq.) and DABC (5-Chloro-l ,3-benzenediamine) were dissolved in N-methylpyrollidone and heated over night at 120C to obtain compound 3 in 85% yield. HI NMR (400, MEOD), d =4.52(8) 5.090V) 7.38 (S) 7.82 (m)), 7.88(m), 7.91 (m), 8.12 9m), 1120-95-2
The synthetic route of 1120-95-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; NEUROPORE THERAPIES, INC.; WRASIDLO, Wolfgang; WO2013/134371; (2013); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem