Analyzing the synthesis route of 932-22-9

As the paragraph descriping shows that 932-22-9 is playing an increasingly important role.

932-22-9, 4,5-Dichloro-3(2H)-pyridazinone is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

932-22-9, Example 35; 5-(3-Cyclobutyl-2,3,4,5-tetrahydro-lH-benzo[d]azepin-7-yloxy)-2-methyl-2H-pyridazin- 3 -one; General synthesis of Example 35:; Step 1: Synthesis of 5-iodo-2H-pyridazin-3-one.; A round-bottom flask contained 4,5-dichloro-2H-pyridazin-3-one (10.0 g, 60.6 mmol) and hydriodic acid (57% in H2O, 80 mL, 606 mmol) was heated at 145 0C for 27 h. After cooled to room temperature, the black precipitation was collected by filtration and was washed with water. The black solid was stirred in water (50 mL) and was added solid sodium thiosulfate (Na2O3S2) in portion until the black color turned grey. The solid material was collected by filtration and was dissolved in 150 mL solvent (MeOH/CH2Cl2 1 :1). It was filtered and the filtrate was concentrated and dried to give 6.13 g (46%) of 5- iodo-2H-pyridazin-3one. 1HNMR (400 MHz, OMS0-d6) delta 13.25 (s, IH), 8.08 (s, IH), 7.54 (s, IH) ; MS (m/z) = 222 (M + 1).

As the paragraph descriping shows that 932-22-9 is playing an increasingly important role.

Reference£º
Patent; CEPHALON, INC.; WO2009/142732; (2009); A2;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem