88497-27-2, 3-Amino-6-bromopyridazine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 6-bromopyridazin-3-amine (10.75 g, 57.5 mmol) in ethyl acetate (150 ml) was added trimethylsilyl 2,2,2-trifluoroacetate (16.88 ml, 98 mmol). After the mixture was stirred for 5 mi triethoxymethane (17.21 ml, 103 mmol) was added. The resulting mixture wasstirred for another five mm, and this was followed by addition of azidotrimethylsilane (12.09 ml,92 mmol). Stirring continued at rt for 2 days, and the mixture was concentrated under reduced pressure. Recrystallization of the residue from ethyl acetate afforded 3-bromo-6-(1H-tetrazol-1- yl)pyridazine. LCMS [M+2+1] = 228.9.
As the paragraph descriping shows that 88497-27-2 is playing an increasingly important role.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; BISWAS, Dipshikha; DING, Fa-Xiang; DONG, Shuzhi; GU, Xin; JIANG, Jinlong; PASTERNAK, Alexander; SUZUKI, Takao; VACCA, Joseph; XU, Shouning; WO2015/103756; (2015); A1;,
Pyridazine – Wikipedia
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